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Symbol Name ID |
Rxra
retinoid X receptor alpha MGI:98214 |
| Darker colors indicate more annotations |
| Human Phenotypes | Lymphadenopathy |
Hepatosplenomegaly |
Peritoneal abscess |
| Disease(s) Associated with RXRA | |||
| pancreatic cancer |
| Mouse Phenotypes | impaired macrophage phagocytosis |
abnormal Langerhans cell morphology |
abnormal T-helper 2 cell morphology |
abnormal peritoneal macrophage morphology |
increased IgG level |
increased IgM level |
abnormal regulatory T cell physiology |
abnormal macrophage activation involved in immune response |
abnormal dendritic cell physiology |
increased autoantibody level |
increased anti-nuclear antigen antibody level |
increased anti-double stranded DNA antibody level |
increased anti-single stranded DNA antibody level |
glomerulonephritis |
skin inflammation |
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| Availability | Mouse Genotype | |||||||||||||||
| Rxrapke/Rxrapke | ||||||||||||||||
| Rxratm1Krc/Rxratm1Krc Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
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| Rxratm2Ipc/Rxratm4Ipc Tg(KRT14-cre)1Ipc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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